After upgrading to NVC for Exchange 5.8 you might receive emails with the following lines:

Norman Message [2004/07/02 13:58:40]
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Application: NVC for Exchange
Node address: 192.168.0.1
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Warning message: Warning: 00b08000 occurred at 00008000. Errortext "Unable to read email stream.". RetCode = 8004010f.

This error can occur when you have both a AVAPI/VSAPI scanner and a gateway-spamfilter on one server. What happens is that during scanning your spamfilter is trying to check whether a user is an existing user. This filter will then take the email to the mailserver and see if the user is valid, or awaits a response from the mailserver that the user is not found in the email domain. The AVAPI/VSAPI scanner sees the email coming through and tries to scan the mail. At that time the mail is retracted by the spamfilter, thus the mailscanner cannot check for viruses.

This is explained, partly, in the following Knowledgebase article written by Microsoft, see point 2:
http://support.microsoft.com/?kbid=179639  
Microsoft claims this is solved when your server is made up-to-date with the latest service packs.