In its security bulletin summary for October 2006 Microsoft reports a total of six new critical vulnerabilities in its operating systems / applications, as well as one important, two moderate and one low.

Critical is Microsoft’s highest vulnerability rating.

A summary describing briefly the vulnerabilities is available from Microsoft’s Security Bulletin Summary for October 2006.
From this page you will also find links to more detailed information in Microsoft's Security Bulletins MS06-057 - MS06-062 (critical), MS06-063 (important), MS06-056 and MS06-065 (moderate), and MS06-064 (low).

Updates that fixes the vulnerabilities are available from Windows automatic update mechanism for systems that support this. Alternatively, one may download updates from http://windowsupdate.microsoft.com.  

Norman advices all affected users to download the security updates as soon as possible, to be protected from potential exploits.